According to the Highway Patrol, James Hensley, 39, of New Richmond, Daniel Frazee, 56, of Bethel and Larry Gillinger, 53, of Fayetteville, were following each other east on US 52.
Hensley, the lead motorist, failed to negotiate a curve to the right and drove left of center where he hit the westbound cement truck, operated by Carl Watson, 58, of Seaman, head on.
The concrete truck overturned and struck the second motorcyclist, Frazee, and the third motorcyclist, Gillinger, were struck by a sliding motorcycle. Two of the motorcycles caught fire.
Hensley and Frazee were pronounced dead at the scene by Dr. Brian Treon the Clermont County Coroner.
Gillinger was transported to University Hospital in Cincinnati by Air Care, and is in critical condition.
Watson was transported to Clermont Mercy Hospital by Pierce Township Life Squad where he was treated and released.
Alcohol use is unknown at this time but is not suspected. The crash remains under investigation by the Ohio State Highway Patrol.